Effe ct of traditional Chinese medicine care combined with cluster care in the care of patients with severe acute pancreatitis

Liu Xiao; Liu Hongfeng; Wang Chenxi; Yang Haiou

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Effe ct of traditional Chinese medicine care combined with cluster care in the care of patients with severe acute pancreatitis

更新时间：2022-11-04

- Effe ct of traditional Chinese medicine care combined with cluster care in the care of patients with severe acute pancreatitis
- Health Medicine Research and Practice Vol. 19, Issue 3, Pages: 82-85(2022)
- 作者机构：
  
  南阳医学高等专科学校第一附属医院普外科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R248.1
- Published：2022，
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Liu Xiao, Liu Hongfeng, Wang Chenxi, et al. Effe ct of traditional Chinese medicine care combined with cluster care in the care of patients with severe acute pancreatitis. [J]. Health Medicine Research and Practice 19(3):82-85(2022)
DOI：

Liu Xiao, Liu Hongfeng, Wang Chenxi, et al. Effe ct of traditional Chinese medicine care combined with cluster care in the care of patients with severe acute pancreatitis. [J]. Health Medicine Research and Practice 19(3):82-85(2022) DOI：

摘要

目的探析在急性重症胰腺炎（SAP）患者治疗过程中实施联合护理方案（中医护理+集束化护理）的临床效果及对患者免疫功能、炎症因子、胰腺损伤生化指标的影响。方法选取2020年7月-2021年6月在河南省某医院接受中西医治疗的84例SAP患者为研究对象

采用随机数字表法将患者分为观察组和对照组

各42例。对照组患者给予集束化护理

观察组患者给予联合护理方案（中医护理+集束化护理）。比较2组患者干预前及干预2周时免疫功能指标[T淋巴细胞亚群（CD4

、CD8

）、CD4

/CD8

]、炎症指标[白细胞（WBC）、C反应蛋白（CRP）、白介素-6（IL-6）、内毒素（LPS）]

、胰腺损伤生化指标[血清淀粉酶（AMY）、脂肪酶（LIP）]。结果干预前

2组患者CD4

、CD8

、CD4

/CD8

水平比较

差异无统计学意义（P

0.05）;干预后

2组患者CD4

、CD4

/CD8

水平高于干预前

且观察组高于对照组;2组患者CD8

水平低于干预前

且观察组低于对照组

差异均有统计学意义（P

0.05）。干预前

2组患者WBC、CRP、IL-6、LPS水平比较

差异无统计学意义（P

0.05）;干预后

2组患者WBC、CRP、IL-6、LPS水平低于干预前

且观察组低于对照组

差异均有统计学意义（P

0.05）。干预前

2组患者AMY、LIP水平比较

差异无统计学意义（P

0.05）。干预后

2组患者AMY、LIP水平低于干预前

且观察组低于对照组

差异均有统计学意义（P

0.05）。结论中西医疗法（柴芩承气汤+乌司他丁）治疗过程中实施联合护理方案（中医护理+集束化护理）

可有效改善患者免疫功能

控制炎症反应

减轻胰腺损伤

值得临床推广应用。

Abstract

Objective To investigate the clinical effect of implementing a combined nursing program（traditional Chinese medicine nursing+cluster nursing） in the treatment of patients with severe acute pancreatitis（SAP） and the effect on patients’ immune function

inflammatory factors

and biochemical indicators of pancreatic injury. Methods Eighty-four patients with SAP who received Chinese and Western medicine treatment in a hospital in Henan from July 2020 to June 2021 were selected as study subjects

and the patients were divided into observation and control groups of 42 cases each using the random number table method. Patients in the control group were given cluster care

and patients in the observation group were given a combined care plan（traditional Chinese medicine care+cluster care）. The immune function indicators [T lymphocyte subsets（CD4

CD8

）

CD4

/CD8

]

inflammation indicators [white blood cells（WBC）

C-reactive protein（CRP）

interleukin-6（IL-6）

lipopolysaccharide（LPS）]

and biochemical indicators of pancreatic injury [serum amylase（AMY）

lipase（LIP）] were compared between the 2 groups of patients before and at 2 weeks of intervention. Results Before the intervention

there was no statistically significant difference between the CD4

CD8

and CD4

/CD8

levels in the 2 groups（P

0.05）; after the intervention

the CD4

and CD4

/CD8

levels in the 2 groups were higher than before the intervention and higher in the observation group than in the control group; the CD8

levels in the 2 groups were lower than before the intervention and lower in the observation group than in the control group. All differences were statistically significant（P

0.05）. Before the intervention

there was no statistically significant difference between the WBC

CRP

IL-6 and LPS levels in the 2 groups（P

0.05）; after the intervention

the WBC

CRP

IL-6 and LPS levels in the 2 groups were lower than before the intervention and lower in the observation group than in the control group

with statistically significant differences（P

0.05）. Before the intervention

there was no statistically significant difference between the AMY and LIP levels in the 2 groups（P

0.05）. After the intervention

the AMY and LIP levels in the 2 groups were lower than before the intervention and lower in the observation group than in the control group

with statistically significant differences（P

0.05）. Conclusion The implementation of combined nursing scheme（traditional Chinese medicine nursing+cluster nursing） in the course of Chinese and Western medicine therapy（Chai Qin Cheng Qi Decoction+Ustatin） has significant clinical effects. It can effectively improve the immune function of patients

control the inflammatory response and reduce pancreatic injury

and is worthy of clinical promotion and application.

关键词

中医护理集束化护理胰腺损伤急性重症胰腺炎免疫因子炎症因子

Keywords

Traditional Chinese medicine nursingCluster nursingPancreatic injurySevere acute pancreatitisImmune factorInflammatory factor

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