Objective To explore the of 3C management in the management of central sterile supply departments（CSSD）.Methods Eighty-six medical instruments received by CSSD during the adoption of routine management in a hospital in Henan Province from March 2019 to March 2020 were selected as the control group

and another 86 medical instruments received by C SSD during the adoption of 3C management in the same hospital from April 2020 to April 2021 were selected as the observation group.The cleaning pass rate

packaging pass rate

sterilization pass rate

instrument cleaning time

management operation cost（human resource cost and operation and maintenance cost） of the 2 groups were compared.The satisfaction of the staff in each clinical department with the 2 management methods was compared.Results The cleaning

packaging and sterilization rates of the observation group were 96.51 %

97.67% and 96.51 %

respectively

which were higher than those of the control group（88.37%

89.53% and 87.21%）

and the differences were statistically significant（P<0.05）.The disinfection and cleaning time of instruments in the observation group was shorter than that in the control group

and the human resources cost and operation and maintenance cost were lower than those in the control group

and the differences were statistically significant（P <0.05）.The observation group had better supply timelines s

service attitude

recovery timeliness and surgical instrument quality scores than the control group in the department staff satisfaction survey

and all differences were statistically significant（P<0.05）.Conclusion The application of 3C management in CSSD management has concrete effect

which can improve the efficiency and quality of instrument cleaning

reduce human resources and operation and maintenance costs

and thus obtain higher satisfaction of departmental personnel

and therefore

it is worthy of clinical promotion and application.