Objective To explore the effect of psychological intervention on the quality of life and emotions of patients with chronic kidney disease. Methods A total of 152 patients with chronic kidney disease admitted to a hospital in Liaoning Province from January 2018 to August 2020 were selected and divided into experimental group（n=77） and control group（n=75） using random number table method. Patients in the control group received conventional nursing interventions on the basis of symptomatic drug therapy

and patients in the experimental group were given psychological intervention on the basis of the control group. The patients in the 2 groups were compared in terms of compliance during treatment and quality of life

SAS and SDS scores

blood urea nitrogen（BUN）

creatinine（Cr）

and glomerular filtration rate（GFR） levels before and after 3 weeks of intervention. Results After the intervention

KDQOL-SFTM symptoms and problems

nephropathy impact

nephropathy stress

work status

cognitive function

social quality

sexual function

sleep

social support scores were higher in the 2 groups than before the intervention

and the experimental group had higher scores than the control group

and the differences were statistically significant（P

<

0.05）. After the intervention

the SAS and SDS scores were lower than those before the intervention

and the experimental group was lower than the control group. The differences were all statistically significant（P

<

0.05）. the BUN and Cr levels were lower than those before the intervention and the experimental group was lower than the control group

and the GFR was higher than before the intervention and the experimental group was higher than the control group

and the differences were all statistically significant（P

<

0.05）. The treatment compliance rate of patients in the experimental group was 98.70%

which was higher than that of the control group（89.33%）

and the difference was statistically significant（χ

2

=4.422

P=0.035）. Conclusion Psychological interventions used in patients with chronic kidney disease can improve patients’ quality of life

mood and treatment compliance

and are beneficial to patients’ renal function recovery.