Clinical efficacy and prognosis of neuroendoscopic hematoma removal via lateral fissure approach in treatment of hypertensive intracerebral hemorrhage

JIANG Yaofeng; SHEN Yang; DONG Yu; WANG Li; LI Yuanyang

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Clinical efficacy and prognosis of neuroendoscopic hematoma removal via lateral fissure approach in treatment of hypertensive intracerebral hemorrhage

更新时间：2022-06-24

- Clinical efficacy and prognosis of neuroendoscopic hematoma removal via lateral fissure approach in treatment of hypertensive intracerebral hemorrhage
- null Issue 6, Pages: 494(2021)
- 作者机构：
  
  南京中医药大学附属南京市中西医结合医院神经外科,江苏,南京,210014
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JIANG Yaofeng, SHEN Yang, DONG Yu, et al. Clinical efficacy and prognosis of neuroendoscopic hematoma removal via lateral fissure approach in treatment of hypertensive intracerebral hemorrhage. [J]. null (6):494(2021)
DOI：

JIANG Yaofeng, SHEN Yang, DONG Yu, et al. Clinical efficacy and prognosis of neuroendoscopic hematoma removal via lateral fissure approach in treatment of hypertensive intracerebral hemorrhage. [J]. null (6):494(2021) DOI：

摘要

目的探讨神经内镜下经外侧裂入路血肿清除术对高血压脑出血（HICH）患者神经功能、炎症因子和预后的影响。方法回顾性分析我院收治的80例HICH患者的临床资料，根据是否采用神经内镜辅助分为A组和B组。A组38例患者给予经外侧裂入路血肿清除术，B组42例患者给予神经内镜下经外侧裂入路血肿清除术。比较2组患者的神经功能、手术指标、炎症因子和预后。结果 B组术中出血量少于A组，血肿清除率高于A组，手术时间短于A组，差异均有统计学意义（P<0.05）。2组术后1 d白介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）、降钙素原（PCT）及C反应蛋白（CRP）水平均较术前升高（P<0.05），但B组低于A组（P<0.05）。2组术后1 d神经元特异性烯醇化酶（NSE）、神经营养因子（NF）、S100B蛋白水平及神经功能缺损程度评分（NDS）较术前均降低（P<0.05），且B组低于A组（P<0.05）。B组预后良好率高于A组（P<0.05），2组病死率比较差异无统计学意义（P>0.05）。结论神经内镜下经外侧裂入路血肿清除术治疗HICH患者，手术效果好，术后机体炎性应激反应较小，可有效减轻患者神经功能损伤，患者预后佳。

Abstract

关键词

经外侧裂入路血肿清除术神经内镜高血压脑出血神经功能炎症因子预后

Keywords

lateral fissure approachhematoma removalneuroendoscopyhypertensive intracerebral hemorrhageneurological functioninflammatory factorsprognosis

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