Clinical effect of neuroendoscopic transsphenoidal approach surgery for pituitary tumors

PU Yi; SHAO Yun; MIAO Wei-feng

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Clinical effect of neuroendoscopic transsphenoidal approach surgery for pituitary tumors

更新时间：2022-06-24

- Clinical effect of neuroendoscopic transsphenoidal approach surgery for pituitary tumors
- null Issue 1, Pages: 31(2022)
- 作者机构：
  
  无锡市人民医院神经外科,江苏,无锡,21402
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PU Yi, SHAO Yun, MIAO Wei-feng. Clinical effect of neuroendoscopic transsphenoidal approach surgery for pituitary tumors. [J]. null (1):31(2022)
DOI：

PU Yi, SHAO Yun, MIAO Wei-feng. Clinical effect of neuroendoscopic transsphenoidal approach surgery for pituitary tumors. [J]. null (1):31(2022) DOI：

摘要

目的探讨神经内镜经蝶窦入路手术治疗垂体瘤的临床效果。方法选取我院收治的垂体瘤患者60例，根据手术方案不同分为观察组（32例）和对照组（28例）。对照组采用神经显微镜经蝶窦入路手术治疗，观察组采用神经内镜经蝶窦入路手术治疗。比较2组手术效果、手术情况、并发症发生情况、手术前后血清PRL及GH水平、T细胞亚群（CD3+、CD4+、CD4+/CD8+）变化情况。结果观察组手术总有效率与对照组比较，差异无统计学意义（P＞0.05）；观察组术后住院时间短于对照组（P<0.05），术中失血量少于对照组（P＜0.05），手术时间组间比较差异无统计学意义（P＞0.05）；术后1 d、术后1个月、术后3个月2组血清PRL、GH水平均逐渐降低（P＜0.05），但组间比较差异无统计学意义（P＞0.05）；2组术后1 d的CD3+、CD4+、CD4+/CD8+均降低（P＜0.05），术后1个月、术后3个月均升高（P＜0.05），且观察组高于对照组（P＜0.05）；观察组并发症发生率与对照组比较，差异无统计学意义（P＞0.05）。结论神经内镜经蝶窦入路手术治疗垂体瘤效果确切，能降低手术创伤，对机体免疫机能影响小，安全性高。

Abstract

关键词

神经内镜神经显微镜经蝶窦入路垂体瘤泌乳素生长激素T细胞亚群

Keywords

neuroendoscopyneuromicroscopytranssphenoidal approachpituitary tumorsprolactingrowth hormoneT cell subsets

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