Outcome of buprenorphine transdermal patch combined with PCIA applied to postoperative analgesia after total knee arthroplasty

LI Hongyan; CHEN Jin; WANG Ya; LI Min; CHEN Xuelian

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Outcome of buprenorphine transdermal patch combined with PCIA applied to postoperative analgesia after total knee arthroplasty

更新时间：2022-06-24

- Outcome of buprenorphine transdermal patch combined with PCIA applied to postoperative analgesia after total knee arthroplasty
- null Issue 5, Pages: 442(2021)
- 作者机构：
  
  宜昌市夷陵医院骨科,湖北,宜昌,443100
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LI Hongyan, CHEN Jin, WANG Ya, et al. Outcome of buprenorphine transdermal patch combined with PCIA applied to postoperative analgesia after total knee arthroplasty. [J]. null (5):442(2021)
DOI：

LI Hongyan, CHEN Jin, WANG Ya, et al. Outcome of buprenorphine transdermal patch combined with PCIA applied to postoperative analgesia after total knee arthroplasty. [J]. null (5):442(2021) DOI：

摘要

目的探讨丁丙诺啡透皮贴联合自控静脉镇痛泵（PCIA）用于膝关节置换术后镇痛的疗效。方法选取因膝关节骨性关节炎行单侧人工膝关节置换术的80例患者，将其随机分为治疗组（术前1 d采用丁丙诺啡透皮贴+PCIA）和对照组（单纯应用PCIA），每组40例。观察比较2组患者术后静态和动态VAS评分、PCIA按压次数、膝关节活动度、补救镇痛药物使用量以及药物不良反应发生率。结果治疗组在术后6 h、12 ｈ、1 d、2 d、3 d的静态和动态VAS评分均明显低于对照组，差异有统计学意义(P<0.05)；而术后4 d、7 d、14 d 2组静态和动态VAS评分比较差异无统计学意义(P>0.05)。治疗组在术后2 d内PCIA按压次数、术后补救镇痛药物使用量均明显少于对照组，差异有统计学意义(P<0.05)。治疗组患者术后３ d、4 d、7 d、14 d膝关节活动度明显大于对照组，差异有统计学意义(P<0.05)；2组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论丁丙诺啡透皮贴联合PCIA应用于膝关节置换术后镇痛是一种安全有效的镇痛方法，对术后疼痛的控制效果显著，可减少患者术后补救镇痛药物的使用，促进膝关节功能早期恢复，且不良反应少。

Abstract

关键词

全膝人工关节置换丁丙诺啡透皮贴镇痛自控静脉镇痛泵

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