Clinical analysis of perinatal COVID-19 in eight pregnant women
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Clinical analysis of perinatal COVID-19 in eight pregnant women
Journal of Chongqing Medical UniversityVol. 45, Issue 7, Pages: 916(2020)
作者机构:
1. 华中科技大学同济医学院附属同济医院1. 妇产科
2. 儿科
3. 检验科,武汉,430030
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基金信息:
DOI:
CLC:
Published:2020,
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Zhang Huiting, Gao Xuan, Feng Ling, et al. Clinical analysis of perinatal COVID-19 in eight pregnant women. [J]. Journal of Chongqing Medical University 45(7):916(2020)
DOI:
Zhang Huiting, Gao Xuan, Feng Ling, et al. Clinical analysis of perinatal COVID-19 in eight pregnant women. [J]. Journal of Chongqing Medical University 45(7):916(2020)DOI:
Clinical analysis of perinatal COVID-19 in eight pregnant women
Objective:To explore and analyze the clinical characteristics and maternal-neonatal outcome of perinatal coronavirus dis-ease 2019(COVID-19). Methods:Clinical data of eight pregnant women who were confirmed with COVID-19 in our hospital from 19th January to 9th February,2020 were retrospectively analyzed. Outcomes were followed up until March 6,2020. General characteristics,clinical features,and maternal and neonatal outcomes were analyzed. Results:①The average age of eight patients was (31.50±2.67) years old,including six multiparas and two primiparas. Six patients experienced onset of illness in late pregnancy,while two in puer-perium. ②Eight patients were in mild situation,with moderate-low temperature(6/8),cough,expectoration(4/8),chest tightness,dizzi-ness,myalgia,and vomiting(1/8);decreased percentage of lymphocytes(6/8),decreased lymphocytes(3/8) and elevated aminotrans-ferase concentrations(2/8);positive lung CT(7/8). ③The range of gestational weeks of delivery was 36+5 to 40+6 weeks. Seven patients had a cesarean section and one had a vaginal delivery. Eight livebirths were recorded. No neonatal asphyxia was observed in newborns. The 36h nasopharyngeal swab in one newborn showed positive COVID-19. Conclusion:Most of patients with perinatal COVID-19 are mild or normal,and short-term maternal and neonatal outcomes are good. Other clinical manifestations are not typical,similar to the non-pregnant. It remains unclear whether COVID-19 can transmit vertically through placenta and consequently lead to short-term or long-term harm to neonates,and data need to be further accumulated.
关键词
围产期新型冠状病毒肺炎临床特点母婴结局
Keywords
perinatal periodcoronavirus disease 2019clinical characteristicsmaternal and neonatal outcomes
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