Objective：To investigate the application effect of Israeli disaster rescue in nurses’ disaster preparedness and analyze the influencing factors for nurses’ disaster preparedness，to provide scientific reference and basis for improving nurses’ disaster rescue abilities and disaster knowledge preparation. Methods：In January 2018，270 nurses were selected from the five grade A tertiary hospi－tals to conduct a survey on nurses’ disaster knowledge preparedness. After the relevant knowledge training of Israeli disaster rescue and implementing the disaster rescue exercise，in June 2018 the nurses were surveyed using a nurses’ disaster knowledge preparedness questionnaire to analyze the intervention effects and the factors affecting the nurses’ knowledge preparedness. Results：After intervention，the scores of all dimensions of the nurses’ disaster preparedness were significantly increased（all P<0.01）：disaster knowledge（4.14±0.44 vs. 4.38±0.86），disaster skill（4.13±0.21 vs. 4.39±0.88），and disaster management（4.02±0.17 vs. 4.44±0.90）；the total score of nurses’ disaster preparedness（197.55±37.53） was at a medium level. The age，education level，working years，professional title，disaster rescue experience，and disaster training of nurses were the main influencing factors for nurses’ disaster preparedness. Conclusion：Israeli disaster rescue has a guiding significance for improving nurses’ disaster preparedness. There is still room for im－provement in nurses’ disaster preparedness in Jiangsu. The hospital should strengthen disaster knowledge training，imple－ment disaster rescue exercise，and learn from international ad－vanced rescue experience to improve nurses’ disaster rescue a－bilities.