Medication Rule of Xin’an Medical Practitioner Wang Renzhi in Treatment of Irregular Menstruation Based on Clustering and Factor Analyses

FU Shufan; XI Ranran; ZHAO Yonglu; LI Jiajie; GUO Jinchen

您当前的位置：

首页 >

文章列表页 >

Medication Rule of Xin’an Medical Practitioner Wang Renzhi in Treatment of Irregular Menstruation Based on Clustering and Factor Analyses

更新时间：2023-04-14

- Medication Rule of Xin’an Medical Practitioner Wang Renzhi in Treatment of Irregular Menstruation Based on Clustering and Factor Analyses
- Journal of Southwest Medical University Vol. 43, Issue 4, Pages: 360-364(2020)
- 作者机构：
  
  安徽中医药大学中医学院
- 作者简介：
- 基金信息：
- DOI：
  CLC： R271.111;R249
- Published：2020，
扫描看全文
[1]付书璠,奚然然,赵永璐,李家劼,郭锦晨.基于聚类与因子分析研究新安医家王任之治疗月经不调用药规律[J].西南医科大学学报,2020,43(04):360-364.

FU Shufan, XI Ranran, ZHAO Yonglu, et al. Medication Rule of Xin’an Medical Practitioner Wang Renzhi in Treatment of Irregular Menstruation Based on Clustering and Factor Analyses. [J]. Journal of Southwest Medical University 43(4):360-364(2020)
[1]付书璠,奚然然,赵永璐,李家劼,郭锦晨.基于聚类与因子分析研究新安医家王任之治疗月经不调用药规律[J].西南医科大学学报,2020,43(04):360-364. DOI：

FU Shufan, XI Ranran, ZHAO Yonglu, et al. Medication Rule of Xin’an Medical Practitioner Wang Renzhi in Treatment of Irregular Menstruation Based on Clustering and Factor Analyses. [J]. Journal of Southwest Medical University 43(4):360-364(2020) DOI：

摘要

目的:使用数据挖掘技术探讨新安医家王任之治疗月经不调的用药规律。方法:从《王任之医案》中选取治疗月经不调的有效处方135首

运用Office 2010、IBM SPSS Modeler 18.0、SPSS Statistics 22.00建立数据库对用药频数、药物组合、用药类别等进行数据挖掘分析。结果:135首处方涉及207味中药

前三类为补血药、活血调经药、补阳药

用药频次达1 769次

频次≥18次共计27味。二项药对使用频次≥26次的药对共32组。由系统聚类分析得到黄芪、甘草、鸡冠花、海螵蛸、五灵脂、香附等9组常用药物组合。由因子分析提取出赤石脂、茜草、地榆、熟地炭、牛膝、泽兰、益母草、卷柏、丹参、柏子仁、熟地黄等20个公因子。结论:王任之辨治月经不调重视肝、肾、气、血的论治

法以养血活血

化瘀为主

并佐疏肝理气、平调阴阳之品

治以补血、化瘀、补阳之剂。

Abstract

Objective: To investigate the medication rule of Xin’an medical practitioner Wang Renzhi in the treatment of irregular menstruation using data mining techniques. Methods: A total of 135 effective prescriptions for the treatment of irregular menstruation were selected from Medical Records of Wang Renzhi

and Office 2010

IBM SPSS Modeler 18.0

and SPSS Statistics 22.0 were used to establish databases and perform a data mining analysis of medication frequency

drug combination

and medication category. Results: These 135 prescriptions involved 207 traditional Chinese medicines

and the top three categories were blood-replenishing medicines

blood circulation-activating and menstruation-regulating medicines

and Yang-tonifying medicines. The medication frequency reached1769 times

and 27 medicines had a frequency of ≥18 times. A total of 32 binomial medicine pairs had a frequency of ≥26 times. The hierarchical cluster analysis obtained 9 combinations of the commonly used medicines including Astragalus membranaceus

Radix Glycyrrhizae

cockscomb

cuttlebone

trogopterus dung

and Rhizoma Cyperi

and the factor analysis obtained 20 common factors including red halloysite

Rubia cordifolia

Sanguisorba officinalis

carbonized prepared Radix Rehmanniae

Achyranthis Bidentatae Radix

Lycopus lucidus

Herba Leonuri

Selaginella tamariscina

Salvia miltiorrhiza

Platycladi seed

and prepared Radix Rehmanniae. Conclusion: In the syndrome differentiation-based treatment of irregular menstruation

Wang Renzhi emphasizes the treatment of the liver

the kidney

and blood and applies the medicines for soothing the liver

regulating Qi

and balancing Yin and Yang.The blood-replenishing

stasis-resolving

and Yang-tonifying medicines are often used for treatment.

关键词

数据挖掘王任之月经不调用药规律

Keywords

Data miningWang RenzhiIrregular menstruationDrug law

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Construction of database in Traditional Chinese Medicine treatment of femoral head necrosis and osteoporosis and mechanism of“treating different diseases with the same method”

Study on the prescription law of Chinese medicine for the treatment of systemic lupus erythematosus containing Rehmannia glutinosa based on data mining

An analysis of clinical medication rule in traditional Chinese medicine treatment of osteoarthritis in recent 20 years

Medication characteristics of East Mountain Villa Basis by Xin’an medical practitioner Ye Xijun:An analysis based on data mining

Medication rules of rheumatism prescriptions from the Xin’an medical practitioner Wang Renzhi: a study based on data mining

Related Author

PENG Wei

HE Lin

TANGDandan

LU Feng

LIU Yicheng

WANG Dan

FENG Ye

GUO Jin-chen

Related Institution

School of Pharmacy，Chengdu University of T..M，Chengdu

Department of Critical Care Medicine，Neijiang Hospital of T..M，Neijiang

Department of Pediatrics of T.C.M,School of T.C.M,Anhui University of Chinese Medicine

Key Laboratory of Xin’an Medical Education Ministry

Department of Hematology, First Affiliated Hospital of Guangzhou University of T..M

⁰