Masquelet technique is a new treatment strategy for bone defects. It repairs bone defects through two stages. In the first stage

the formation of membranes is induced surgically; in the second stage

the defect was filled with autogenous bone graft. Compared with other treatment strategies for bone defects

Masquelet technique is more practical

and has higher success rate and reliability. Therefore

it has been gradually applied to bone defects caused by trauma

infection

tumor

and other reasons. This article reviews the application and progress of Masquelet technology in repairing bone defects around the world

in order to better guide the clinical application.