LIN Guangyao, WANG Yongzhou. Research advances in polycystic ovary syndrome and insulin resistance. [J]. Journal of Southwest Medical University 43(3):310-313(2020)
LIN Guangyao, WANG Yongzhou. Research advances in polycystic ovary syndrome and insulin resistance. [J]. Journal of Southwest Medical University 43(3):310-313(2020)DOI:
Research advances in polycystic ovary syndrome and insulin resistance
摘要
多囊卵巢综合征(polycystic ovary syndrome
PCOS)
是女性最常见的以代谢和内分泌紊乱为特征的疾病
也是引起胰岛素抵抗和2型糖尿病的重要原因。稳态模型评估胰岛素抵抗(homeostatic model assessment-insulin resistance
Polycystic ovary syndrome is the most common disease characterized by metabolic and endocrine disorders in women and it is also an important cause of type 2 diabetes and insulin resistance. Homeostatic model assessment-insulin resistance and oral glucose tolerance test are the most commonly used methods for detecting insulin resistance. Weight loss and effective lifestyle intervention play an important role in improving insulin resistance in PCOS. Meanwhile
metformin is recommended as the first-line drug for the treatment of PCOS with insulin resistance by mainstream guidelines and consensus statements. This article reviews the pathogenesis of PCOS and insulin resistance and related diagnosis and treatment methods.