Objective:To investigate the risk factors for preoperative sudden death in patients with Stanford A acute aortic dissection

and to predict the severity of Stanford A aortic dissection and develop accurate treatment plan before surgery. Methods:A total of 111 patients with Stanford A aortic dissection who were admitted to the Intensive Care Unit of Department of Cardiothoracic Surgery in our hospital from July 2015 to November 2019 were selected

among whom 15 patients abandoned treatment and 96 patients received treatment and were enrolled in this study. According to whether preoperative sudden death was observed

the 96 patients were divided into sudden death group with 37 patients（who died before surgery）and control group with 59 patients（who underwent surgical treatment successfully）. The clinical data of the patients were collected for statistical analysis. Results:A one-way analysis of variance showed that there were significant differences between the two groups in age

systolic pressure

diastolic pressure

pulse pressure

smoking

white blood cell count（WBC）

neutrophils

D-dimer

fibrinogen

and prothrombin time（P < 0.05）. The factors with significant correlation were included in the multivariate logistic regression analysis

and the results showed significant differences in age

systolic pressure

and WBC

which were positively correlated with sudden death. Conclusion:Age

systolic pressure

and WBC are independent risk factors for preoperative sudden death in patients with Stanford A acute aortic dissection. Clinicians should pay special attention to these factors at initial diagnosis

so as to select appropriate surgery and treatment.