Objective:To investigate the clinical significance of renal arterial blood flow parameters combined with cystatin C（CysC） in evaluating renal injury in patients with preeclampsia. Methods:A total of 30 patients with mild preeclampsia

30 patients with chronic hypertension and preeclampsia

and 30 patients with severe preeclampsia

who were hospitalized and gave birth in Department of Obstetrics in our hospital from January 2016 to January2017

were enrolled as groups A

B

and C

respectively

and 30 healthy pregnant women were enrolled as control group（group D）. Related blood flow parameters of the renal interlobar arteries were measured for all subjects

including peak systolic velocity（PSV）

end-diastolic velocity（EDV）

acceleration time（AT）

and systolic acceleration（SA）

and the biochemical parameters including uric acid（UA） and CysC were measured. The correlation between renal blood flow parameters and biochemical parameters was analyzed. Results:Compared with group D

groups A

B

and C had significantly lower PSV

EDV

and SA and a significantly higher AT（P < 0.05）

and compared with group A

groups B and C had significantly lower PSV

EDV

and SA and a significantly higher AT（P < 0.05）. Groups B and C had significantly higher UA and CysC than groups D and A（all P < 0.05）

and group A had a significantly higher level of CysC than group D（P < 0.05）. UA and CysC were negatively correlated with PSV

EDV

and SA and were positively correlated with AT（P < 0.05）. Compared with UA

CysC had higher correlation with renal blood flow parameters. Conclusion:Renal arterial blood flow parameters combined with CysC have a certain clinical value in evaluating renal function in patients with preeclampsia.