Objective Analyzing the epidemiological characteristics and the main virus types of confirmed HFMD in Zhuzhou city from 2009 to 2018

the reference was provided for prevention and control of HFMD in the whole city. Methods The data of laboratory diagnosis of HFMD in China’s disease prevention and control information system was used to analyze the epidemiological characteristics

and the difference in the reported incidence of CoxA16-type

the other enterovirus-type and EV71-type HFMD by every year

the difference in the reported incidence of all types of HFMD in urban areas and counties

the difference in regional and county critical and mortality

were compared by Chi-square test. Results From 2009 to 2018

a total of 7

258 confirmed cases of HFMD were reported in the city

with an average reported incidence of 17.04/105. The average reported incidences of Cox A16-type

the other enterovirus-type and EV71-type HFMD are 1.68/105

3.15/105

and 12.21/105.The confirmed cases mainly occurred in April to July and October to December

the same months as the main cases of EV71-type. The proportion of reported confirmed HFMD between men and women was 1.32∶1.The concentration of confirmed HFMD among children under the age of 5（95.54%）;The highest incidence of each confirmed cases was reported in the 1-

<

2 age group;the number of diagnosed HFMD in each district ranged from 3.24/105 to 53.34/105.The average reported morbidity of diagnosed HFMD in urban areas was higher than that in the counties

and the difference was statistically significant（χ

2

=7 333.36

P=0.000）.The severe case rate of confirmed cases of HFMD was 1.14%

and the severe case fatality rate was 18.07%;the severe case rate of confirmed cases in urban and county areas was not statistically significant（χ

2

=1.13

P=0.267）

The severe case fatality rate of confirmed cases was statistically significant（χ

2

=10.63

P =0.000）. Conclusion The dominant pathogen of HFMD in Zhuzhou City is EV71 virus

which infections account for the majority of confirmed cases

severe cases and death cases. Controlling EV71 infection of HFMD will effectively reduce the reported incidence of HFMD in Zhuzhou City

and reduce severe cases and deaths of HFMD.