Zou Li, Feng Li, Chen Dan. Clinical analysis of pancytopenia induced by low-dose methotrexate treatment one case with psoriasis. [J]. Health Medicine Research and Practice 17(5):90-92(2020)
Zou Li, Feng Li, Chen Dan. Clinical analysis of pancytopenia induced by low-dose methotrexate treatment one case with psoriasis. [J]. Health Medicine Research and Practice 17(5):90-92(2020)DOI:
Clinical analysis of pancytopenia induced by low-dose methotrexate treatment one case with psoriasis
摘要
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正
>
甲氨蝶呤(MTX)是一种免疫调节剂。该药于20世纪40年代末用于抗肿瘤治疗
后被推荐用于对常规治疗无反应的重度银屑病、银屑病性关节炎或类风湿关节炎。众所周知
大剂量MTX容易导致患者出现许多不良反应
且MTX在临床上的安全使用剂量一直是医学界研究的重点课题。虽然MTX导致全血细胞减少的情况较少见
但因其较高死亡率成为了临床的难点问题
[1-2]
。本研究以重庆市某医院收治的经小剂量甲氨蝶呤治疗出现全血细胞减少症的1例患者为研究对象
分析导致患者出现全血细胞减少的原因
现报道如下。
Abstract
<
正
>
甲氨蝶呤(MTX)是一种免疫调节剂。该药于20世纪40年代末用于抗肿瘤治疗
后被推荐用于对常规治疗无反应的重度银屑病、银屑病性关节炎或类风湿关节炎。众所周知
大剂量MTX容易导致患者出现许多不良反应
且MTX在临床上的安全使用剂量一直是医学界研究的重点课题。虽然MTX导致全血细胞减少的情况较少见
但因其较高死亡率成为了临床的难点问题
[1-2]
。本研究以重庆市某医院收治的经小剂量甲氨蝶呤治疗出现全血细胞减少症的1例患者为研究对象
分析导致患者出现全血细胞减少的原因
现报道如下。
关键词
甲氨蝶呤全血细胞减少骨髓抑制银屑病肾功能发病率
Keywords
MethotrexatePancytopeniaBone marrow suppressionPsoriasisRenal functionIncidence of morbidity
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Related Author
Liang Caige
Ma Dongdong
Zheng Chenchen
Xiong Ying
Yuan Fang
Fan Jing
Su xiaoyan
Jiang Pinghu
Related Institution
Emergency Medicine Dept., the First Affiliated Hospital of Henan University of Science and Technology
Department of Pediatrics, Panjin Liaoyou Gemstone Flower Hospital
Department of Nephrology, Affiliated Hospital of Liaoning University of Chinese Medicine
Department of Endocrinology, Fujian Provincial Hospital
Hemodialysis Center, Zhengzhou Central Hospital Affiliated to Zhengzhou University