Wang Jin, Dong Xiangyu. Research progress on the mechanism of Kawasaki disease and virus infection. [J]. Health Medicine Research and Practice 17(4):86-89(2020)
Wang Jin, Dong Xiangyu. Research progress on the mechanism of Kawasaki disease and virus infection. [J]. Health Medicine Research and Practice 17(4):86-89(2020)DOI:
Research progress on the mechanism of Kawasaki disease and virus infection
摘要
川崎病(KD)是一种儿童时期获得性的心脏疾病
表现为血管炎综合征
常累及冠状动脉。虽然KD病因和整个发病机制尚不清楚
但已有的证据表明KD的发病机制与机体对各种病毒或微生物的免疫应答失调密切相关
特别是与病毒感染相关性强。根据临床和实验证据
本文就与KD相关的病毒感染研究进展作一综述
以期为今后深入研究KD发病机制提供参考。
Abstract
Kawasaki disease is a childhood acquired heart disease characterized by vasculitis syndrome
which often involves coronary artery disease. Although the etiology and the whole pathogenesis are not clear
there is evidence that the pathogenesis of KD is closely related to the imbalance of immune response to various viruses or microorganisms. In particular
it has a strong correlation with virus infection. According to the clinical and experimental evidence
this paper reviews the research progress of virus related to KD.