Objective To assess the effect of periodontal basic treatment on the inflammatory control

serum levels of inflammatory markers and glucose metabolism in patients with chronic periodontitis complicated by type 2 diabetes.Methods Sixty patients with both chronic periodontitis and type 2 diabetes were enrolled from a Hunan hospital between May 2015 and January 2017.Using a random number table

patients were randomized into the trial group（n=30）or the control group（n=30）.Patients in the trial group received routine treatment plus periodontal basic treatment

while those in the control group received routine treatment alone.The parameters reflecting the severity of periodontal inflammation and glucose metabolism as well as the serum levels of inflammatory markers were assessed and compared.Results Before treatment

the gingival bleeding index（GBI）and probing depth（PD）were similar between the two groups（P>0.05）;after treatment

the GBI and PD were improved in both groups

but significantly better in the trial group compared with those in the control group（P<0.05）.At baseline

the serum levels of tumor necrosis factorα（TNF-α）

hypersensitive C-reactive protein（CRP）

fasting plasma glucose（FPG）and glycosylated hemoglobin（HbA1 c）were comparable between the two groups（P >0.05）;after treatment

the serum TNF-α

CRP

FPG and HbA1 clevels were reduced in both groups

but significantly lower in the trial group compared with those in the control group（P<0.05）.Conclusion For patients with chronic periodontitis complicated by type 2 diabetes

periodontal basic treatment could greatly improve the periodontal status

alleviate both local and systemic inflammatory response

and facilitate glucose control

which is worthy of clinical use.