Objective To understand the effects of coke oven emissions that contained polycyclic aromatic compounds（PAHs）on nerve function and neurotransmitters in coke oven workers.Methods 100 adult male coke oven workers as contact group and 100 controls were selected.After 2groups were balanced in related factors the basic information and subjective symptoms of occupational exposure population were collected through questionnaire.In the plasma the levels of dopamine（DA）

adrenaline（AD）

noradrenaline（NE）and serotonni（5-HT）were measured by high performance liquid chromatography with electrical chemical detector.Results There were more workers in the contacts group had the symptoms of sneeze

sore throat

loss of appetite and rash than the control group and the difference was statistical significant（P<0.05）.The Proportion of contacts having difficulties in concentrating energy or memorizing was higher than that of controls in the past year.The levels of NE

DA

5-HT in coke oven workers were significantly higher than the controls（P<0.05）

while the level of AD in plasma was no significant different（P>0.05）.Conclusion The coke oven emissions that contained PAHs may affect the nerve function and neurotransmitters in plasma of exposure population.