Efficacy of Low-dose Metronidazole Combined with Lactic Acid Bacteria in the Treatment of Gestational Trichomonas Vaginitis

Jiang Li

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Efficacy of Low-dose Metronidazole Combined with Lactic Acid Bacteria in the Treatment of Gestational Trichomonas Vaginitis

更新时间：2021-08-23

- Efficacy of Low-dose Metronidazole Combined with Lactic Acid Bacteria in the Treatment of Gestational Trichomonas Vaginitis
- Health Medicine Research and Practice Vol. 13, Issue 5, Pages: 40-42(2016)
- 作者机构：
  
  沈阳市妇婴医院温馨二病房
- 作者简介：
- 基金信息：
- DOI：
  CLC： R714.259
- Published：2016，
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[1]姜丽.小剂量甲硝唑联合乳酸菌治疗妊娠期滴虫性阴道炎的疗效分析[J].保健医学研究与实践,2016,13(05):40-42.

Jiang Li. Efficacy of Low-dose Metronidazole Combined with Lactic Acid Bacteria in the Treatment of Gestational Trichomonas Vaginitis. [J]. Health Medicine Research and Practice 13(5):40-42(2016)
[1]姜丽.小剂量甲硝唑联合乳酸菌治疗妊娠期滴虫性阴道炎的疗效分析[J].保健医学研究与实践,2016,13(05):40-42. DOI：

Jiang Li. Efficacy of Low-dose Metronidazole Combined with Lactic Acid Bacteria in the Treatment of Gestational Trichomonas Vaginitis. [J]. Health Medicine Research and Practice 13(5):40-42(2016) DOI：

摘要

目的探讨小剂量甲硝唑联合乳酸菌治疗妊娠期滴虫性阴道炎的临床疗效。方法选取2014年9月-2016年3月沈阳市某医院收治的140例妊娠期滴虫性阴道炎患者作为研究对象

随机分为对照组（n=65）与观察组（n=75）。对照组患者给予口服小剂量甲硝唑治疗

观察组患者在对照组基础上加用乳酸菌阴道胶囊治疗。比较2组患者临床治疗效果、不良反应发生情况、治疗6个月时复发情况及简明健康调查问卷（SF-36）综合分数。结果观察组患者治疗总有效率、SF-36综合分数均明显高于对照组

差异有统计学意义（P<0.05）;观察组患者不良反应发生率为1.33%

对照组患者不良反应发生率为1.54%

差异无统计学意义（P>0.05）。治疗6个月时

观察组无复发病例

对照组患者复发率为18.46%

差异具有统计学意义（P<0.05）。结论小剂量甲硝唑联合乳酸菌治疗妊娠期滴虫性阴道炎效果显著

且提高了患者的生活质量

值得临床推广应用。

Abstract

Objective To assess the clinical efficacy of low-dose metronidazole combined with lactic acid bacteria in treating gestational trichomonas vaginitis.Methods A total of 140 women diagnosed with gestational trichomonas vaginitis were recruited from a Shenyang hospital during Sep.2014 to Mar.2016.Patients were randomized into the trial group（n=75

low-dose metronidazole+lactic acid bacteria vaginal capsule）and the control group（n=65

low-dose metronidazole alone）.The total effective rate

the incidence of adverse events

the recurrence rate and the Short Form 36 Health survey Questionnaire（SF-36）score at 6 months were compared between the two groups.Results The total effective rate and the SF-36 score in the trial group were significantly higher compared with the control group（P<0.05）.The incidence of adverse events was similar between the trial group and the control group（1.33% vs.1.54%

P>0.05）.At 6months

no relapse was observed in the trial group

while the recurrence rate was up to 18.46%in the control group（P<0.05）.Conclusion Low-dose metronidazole combined with lactic acid bacteria is very effective in treating gestational trichomonas vaginitis

which may improve the quality of life of patients and deserve more widespread clinical use.

关键词

乳酸菌甲硝唑滴虫性阴道炎妊娠期

Keywords

Lactic acid bacteriaMetronidazoleTrichomonas vaginitisPregnancy

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Related Institution

Department of Obstetrics and Gynecology, the First Affiliated Hospital of Henan University

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Training Center of Department of Rehabilitation and Health Care,Guangzhou Health Science College

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