This dissertation analyzes and summarizes current situations of research on the action and mechanism of opioid peptides and receptors in（exercise preconditioning）EP myocardial protection through the method of documentation.It deems that the opioid peptides and receptors are involved in the process of EP myocardial protection

and the mechanism exerts its effects in the early preconditioning（EPC）and delayed preconditioning（DPC）of the EP.Cell signal transduction pathway may be released for endogenous opioid peptides（EOP）

activate protein kinase dominated by protein kinase C（PKC）

thereby regulating effect factors and exerting effects on myocardial protection.EP substantially induces the endogenous protection mechanism of organism by means of exercise stress

thus improving myocardial ischemia.