An Analysis of the Value of High Sensitive C-reactive Protein for Predicting Coronary Heart Disease

TONG Kai-miao1 LI Ying2 LUO Yi-wei2

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An Analysis of the Value of High Sensitive C-reactive Protein for Predicting Coronary Heart Disease

更新时间：2021-08-23

- An Analysis of the Value of High Sensitive C-reactive Protein for Predicting Coronary Heart Disease
- Health Medicine Research and Practice Vol. 8, Issue 2, Pages: 44-45(2011)
- 作者机构：
  
  1. 同济大学研究生院
  2. 同济大学附属东方医院
- 作者简介：
- 基金信息：
- DOI：
  CLC： R541.4
- Published：2011，
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[1]童开妙,李莹,罗轶伟.超敏C反应蛋白预测冠心病的价值分析[J].保健医学研究与实践,2011,8(02):44-45+52.

TONG Kai-miao1 LI Ying2 LUO Yi-wei2. An Analysis of the Value of High Sensitive C-reactive Protein for Predicting Coronary Heart Disease. [J]. Health Medicine Research and Practice 8(2):44-45(2011)
[1]童开妙,李莹,罗轶伟.超敏C反应蛋白预测冠心病的价值分析[J].保健医学研究与实践,2011,8(02):44-45+52. DOI：

TONG Kai-miao1 LI Ying2 LUO Yi-wei2. An Analysis of the Value of High Sensitive C-reactive Protein for Predicting Coronary Heart Disease. [J]. Health Medicine Research and Practice 8(2):44-45(2011) DOI：

摘要

目的探讨血清超敏C反应蛋白（hs-CRP）与冠心病（CHD）的关系

分析其对CHD是否有预测价值。方法对240例拟诊为心血管疾病的患者行冠脉造影（CAG）检查和血清hs-CRP检测

进行对比分析。结果按hs-CRP检测的浓度分成0～<3 mg/L、3～<9 mg/L、≥9 mg/L 3个区域

其对应的CHD的检出率分别为54.17%、63.79%、70.97%

0～<3 mg/L与≥9 mg/L之间差异有检出意义（χ2=4.80

P<0.05）

CHD患者hs-CRP异常率达55.48%

非CHD患者为41.49%

差异有统计学意义（χ2=4.48

P<0.05）

而3～<9 mg/L与0～<3 mg/L或≥9 mg/L之间差异均无统计学意义（P>0.05）。结论血清hs-CRP是CHD的一个危险因素

与CHD的发生、发展及预后密切相关

可作为CHD早期诊断及病情监测指标

有一定的临床推广价值。

Abstract

Objective To explore the relationship between serum high sensitive C-reactive protein（hs-CRP） and coronary heart disease（CHD）

and to analyze if hs-CRP has predictive value for CHD.Method 240 suspected cases of cardiovascular disease received the examination of coronary angiography and the test of serum hs-CRP

and the results were compared and analyzed.Results Three parts 0～<3 mg/L

3～<9 mg/L and ≥9 mg/L after division according to the concentration tested by hs-CRP and their corresponding detection rates of CHD were 54.17%

63.79% and 70.97% respectively.The difference between 3～<9 mg/L and 0～<3 mg/L was of detection significance（χ2=4.80

P<0.05）.The abnormal rate of hs-CRP in patients with CHD was 55.48%

and non-CHD patients 41.49% and the difference was statistically significant（χ2=4.48

P<0.05）.The difference between 3～<9 mg/L and 0～<3 mg/L or ≥9 mg/L was not statistically significant（P>0.05）.Conclusion Serum hs-CRP is a risk factor of CHD and is closely related to the occurrence

development and predictability of CHD.It can be used as the monitoring index of early diagnosis and condition of CHD

worthy of certain clinical promotion.

关键词

hs-CRPCAGCHD预测

Keywords

Hs-CRPCAGCHDPrediction

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