Objective The analysis aims to enhance the knowledge of GERD

study its clinical characteristics

distinguish the method of diagnosis and treatment

and reduce misdiagnosis and wrong treatment.Method A retrospective study was made on 16 patients at Peking University’s 102 Clinic and the Center of Cardiovascular Disease.The clinical records and the diagnosis made by those clinics were analyzed to find out the reasons of misdiagnosis.Results GERD is a common gastrointestinal disease

its symptom is not distinctive

and its patients are easily diagnosed as coronary heart disease angina

especially with middle and old aged patients when they feel pain at heart.Conclusion The main reason of misdiagnosis of GERD is due to physicians’ lack knowledge of its clinical characteristics.