Studies of Neuropeptide Y and Its Receptors as Target in Obesity

ZHAO Qing HU Chang-hua

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Studies of Neuropeptide Y and Its Receptors as Target in Obesity

更新时间：2021-08-23

- Studies of Neuropeptide Y and Its Receptors as Target in Obesity
- Health Medicine Research and Practice Issue 2, Pages: 70-73(2008)
- 作者机构：
  
  1. 西南大学药学院现代生物医药研究所
  2. 西南大学药学院现代生物医药研究所重庆400715
- 作者简介：
- 基金信息：
- DOI：
  CLC： R589.2
- Published：2008，
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[1]赵青,胡昌华.神经肽Y及其受体作为肥胖治疗靶点的研究进展[J].保健医学研究与实践,2008(02):70-73.

ZHAO Qing HU Chang-hua. Studies of Neuropeptide Y and Its Receptors as Target in Obesity. [J]. Health Medicine Research and Practice (2):70-73(2008)
[1]赵青,胡昌华.神经肽Y及其受体作为肥胖治疗靶点的研究进展[J].保健医学研究与实践,2008(02):70-73. DOI：

ZHAO Qing HU Chang-hua. Studies of Neuropeptide Y and Its Receptors as Target in Obesity. [J]. Health Medicine Research and Practice (2):70-73(2008) DOI：

摘要

肥胖是人类健康的一个严重威胁

它与神经肽Y（neuropeptide Y

NPY）密切相关。NPY通过其受体介导来刺激食欲、增加体重从而导致肥胖。本文对NPY及其受体的作用机制、治疗肥胖药物潜在靶点的开发及潜在药物先导化合物的研究情况作一简要概述。

Abstract

Obesity is a very seriously danger for human’s health

NPY is implicated in energy homeostasis

and contributes to obesity.NPY receptors are involved in mediating NPY-induced stimulation of food intake and body weight gain.This article will not only expatiate the mechanisms which NPY and its receptors play in obesity’s occurrence and development

but also introduce the potential targets and drug precursors in discovery of the drugs to therapy obesity.

关键词

肥胖神经肽YNPY受体激动剂抑制剂药靶

Keywords

obesityNeuropeptide YNeuropeptide Y receptorAgonistAntagonistsDrug target

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