Objective To investigate the relationship between plasma fibrinogen level and recurrent spontaneous abortion.Method The levels of plasma fibrinogen were determined by turbidimetry in 30 patients with recurrent spontaneous abortion（RSA） and in 30 healthy controls（CON）.Results The plasma fibrinogen level in RSA group was significantly lower than in CON groups（2.31±0.57）g/L vs（3.08±0.57）g/L

（p<0.05）.The plasma fibrinogen level in more than two abortion group was significantly lower than in twice abortion group significantly（2.59±0.53）g/L vs（1.86±0.24）g/L

（p<0.05）;No significant difference was found in plasma fibrinogen level between the early abortion group and the later abortion group（p>0.05）.Conclusion The low level of fibrinogen is a probably risk factor of recurrent spontaneous abortion.The number of abortion is an important factor of fibrinogen levels affect.No close association of plasma fibrinogen level with recurrent spontaneous abortion was found.