The Developments of Researches in Lung Resistance Protein in Multidrug Resistance of Cancer Cells

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The Developments of Researches in Lung Resistance Protein in Multidrug Resistance of Cancer Cells

更新时间：2021-08-20

- The Developments of Researches in Lung Resistance Protein in Multidrug Resistance of Cancer Cells
- Health Medicine Research and Practice Issue 1, Pages: 74-77(2008)
- 作者机构：
  
  重庆交通大学医院,重庆,400074
- 作者简介：
- 基金信息：
- DOI：
  CLC： R730.5
- Published：2008，
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[1]李醒.肺耐药蛋白与肿瘤细胞多药耐药的研究进展[J].保健医学研究与实践,2008(01):74-77.

LI Xing. The Developments of Researches in Lung Resistance Protein in Multidrug Resistance of Cancer Cells. [J]. Health Medicine Research and Practice (1):74-77(2008)
[1]李醒.肺耐药蛋白与肿瘤细胞多药耐药的研究进展[J].保健医学研究与实践,2008(01):74-77. DOI：

LI Xing. The Developments of Researches in Lung Resistance Protein in Multidrug Resistance of Cancer Cells. [J]. Health Medicine Research and Practice (1):74-77(2008) DOI：

摘要

肺耐药蛋白是一种110KD的蛋白。研究发现肺耐药蛋白就是在人正常组织和肿瘤细胞中广泛分布的穹隆体主蛋白

且具有组织特异性。肺耐药蛋白直接或间接介导了多种肿瘤细胞多药耐药的产生

可作为治疗预后评判的指标

肺耐药蛋白高提示预后不良。

Abstract

Lung Resistance Protein（LRP）is one kind of 110KD protein.Researches had indicated LRP is Major Vault Protein（MVP）

which commonly existed in human normal cells and the cancer cells.LRP had tissue specificity.LRP induced cancer cells resist to multidrugs in direct or indirect ways.LRP may be of predictive value in treatments of carcinomas

and high expression of LRP was correlated with bad prognosis.

关键词

多药耐药肺耐药蛋白穹窿体主蛋白

Keywords

Multidrug resistanceLung resistance proteinMajor vault protein

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