Objective To demonstrate the additive effect of samshu and coffee and then explore the influence of asparagus on the former result from the hereditary poisonous aspect

in order to provide rational diet guidance to the public. Method Calculating the micronucleus rate of vicia faba while they are cultured by the mixture of samshu and coffee

then by asparagus

samshu and coffee through the micronucleus test technique. Results Micronucleus rate of the mixture of samshu and coffee is（63.00±14.00）‰

which much higher than the rate of samshu（17.67±3.51）‰ or the rate of coffee（24.00±3.60）‰

respectively; micronucleus rate of the mixture of samshu

coffee and asparagus is is（44.33±10.97）‰

and it is noteworthy lower than the mixture without asparagus. Conclusion The poisonous heredity of samshu and coffee has additive effect; in addition

asparagus juice has a positive influence on reducing the micronucleus rates induced by the former two drinks

leading to our suggestion that asparagus may have an advantage on relieving hereditary damage.