Objective       To investigate the efficacy and complications of diminution of the ureathral functional area (DUFA) in treating female primary bladder neck obstruction (FPBNO).       Methods      A  total of 122 patients

who were diagnosed with FPBNO by international prostate symptom score (IPSS) evaluation and urodynamic examination

underwent surgical procedur

es in our institution from May 2009 to April 2015. The perioperative and follow-up data

including operative time

hemorrhage in operation

IPSS

maximum urine flow rate (Qmax)

residual urine volume

ureathral functional area (UFA)

detrusor muscle pressure and complications

were prospectively investigated.    Results         All of the operations were completed uneventfully. The median operative time was 19.7±8.3 min (ranged 16~27 min). Hemorrhage in operation was 15.2±6.9 mL. Postoperative sixmonth follow-up data were available for 122 patients. The mean IPSS decreased from 25.6±8.2 to 4.5±2.6. The Q

max

increased from preoperative 7.5±3.8 mL/s to postoperative 25.9±8.3 mL/s. The mean residual urine volume was decreased from 164.1±86.8 mL to 17.4±9.1 mL. The mean UFA decreased from 1 392.9±697.6 mmcmH

2

O to 654.6±211.3 mmcmH

2

O. The mean detrusor muscle pressure decreased from 36.5±12.1 cmH

2

O to 18.6±6.3 cmH

2

O. All the differences between the preoperative and postoperative values were significant (P0.01). Conclusion     DUFA can decrease the UFA

release the obstruction and maintain the continence

so it is a safe and effective treatment method for FPBNO.