Zhuang Wei,Qin Mingxin,Pan Wencai,Jin Gui Sun Jian,Yan Qingguang,Ning Xu,Li Gen,Peng Bin.Detection of acute cerebral ischemia in rabbits by magnetic induction phase shift spectroscopy[J].J Amry Med Univ (J Third Mil Med Univ),2016,38(16):1837-1842.
Zhuang Wei,Qin Mingxin,Pan Wencai,Jin Gui Sun Jian,Yan Qingguang,Ning Xu,Li Gen,Peng Bin.Detection of acute cerebral ischemia in rabbits by magnetic induction phase shift spectroscopy[J].J Amry Med Univ (J Third Mil Med Univ),2016,38(16):1837-1842.DOI:
Detection of acute cerebral ischemia in rabbits by magnetic induction phase shift spectroscopy
Objective To propose a new method for early detection of acute cerebral ischemia in rabbits
and establish an early diagnosis system for acute cerebral ischemia. Methods The cerebral ischemia rabbit model was established by bilateral carotid artery occlusion. The rabbits were divided into nonligation group
unilateral ligation group and bilateral ligation group. The rabbits of the 3 groups were detected for 1 h with a detection system based on magnetic induction phase shift spectroscopy (MIPSS). Results The results showed that under characteristic frequency (CF)
within 1 h
the average phase shift of the nonligation group was -0.195°±0.099°
the average phase shift of the unilateral ligation group was -4.862°±1.150°
and the average phase shift of the bilateral ligation group was -9.303°±3.186°. The average phase shift of the unilateral ligation group and the bilateral ligation group was increased significantly compared with the control group(P0.05)
and the average phase shift of the bilateral ligation group was increased significantly compared with the unilateral ligation group (P0.05). Conclusion Detection system based on MIPSS implements the early diagnosis of acute cerebral ischemia in the rabbits
and can be used for distinguishing the varied ischemic severity in the rabbits.