Abuse of antibiotics has become a troublesome issue for clinical medicine

and the researches on new antimicrobial agents such as graphene materials (GMs) have attracted more concerns with the progress of nanomedicine. GMs are considered as a kind of new nanomaterials with efficient antimicrobial activities

and have promising applications in medical frontiers such as biosensors and biotherapy. This article discussed the physicochemical properties of GMs

experimental surroundings

selected microorganisms

and interaction between GMs and selected microorganisms to explore controversial antimicrobial activities. In addition

several mechanisms of the antimicrobial activities of GMs were deeply analyzed

and the prospects and probable challenges of GMs in the field of antibacterial agents were also proposed.