Objective      To detect the plasma levels of 3-mercaptopyruvate sulfurtransferase (3MST) and beta amyloid protein (Aβ

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) in acute cerebral infarction patients

and their relationship with infarct volume and severity of neurologic deficits.       Methods      Fifty-two patients with acute cerebral infarction admitted in our hospital from October 2013 to November 2014 were recruited in this study

and another 35 healthy i

ndividuals taking physical examination at same period served as normal control. The plasma levels of 3MST and Aβ

42

were detected in the both groups by ELISA

and the relationship of plasma 3MST and Aβ

42

contents with cerebral infarction was analyzed.       Results      The plasma content of 3-MST was significantly lower in the acute cerebral infarction patients than the normal control (3.67±0.29 vs 4.98±0.30 ng/mL

P0.05)

but that of Aβ

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was obviously high (44.52±2.92 vs 15.77±1.71 pg/mL

P0.05). Among the patients with acute cerebral infarction

the plasma content of 3-MST was decreased with the enlargement of cerebral infarction volume and the increase of National Institutes of Health Stroke Scale (NIHSS) score

while that of Aβ

42

was increased with the changes.       Conclusion      The plasma level of 3-MST is abnormally decreased

while that of Aβ

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significantly elevated in acute cerebral infarction patients

and the changes may be related with the severity of neurologic deficits and infarct volume.