Objective      To investigate the differences of cognitive dysfunction among different motor subtypes of Parkinson’s disease (PD).       Methods      A total of 128 patients with PD were enrolled randomly from November 2012 to November 2014 in inpatient and outpatient of department of neurology our hospital

and divided into tremor-dominant (TD) group (n=38)

akinetic-rigid (AR) group (n=47)

and mixed group (n=43) according to the Unified Parkinson’s disease rating scale (UPDRS)-Ⅲ motor scores. The cognitive function of all the patients was assessed with the mini-mental state examination (MMSE) and Montreal cognitive assessment (MoCA) scales.       Results      The average scores of MMSE and MoCA of all the patients were 26.94±3.262 and 21.37±5.110

respectively (r=0.761

P0.01). MMSE total score and single-item score had no differences among the 3 groups (P0.05). MoCA total score (P=0.012)

language item (P=0.018) and delayed memory item (P=0.003) showed statistically significant differences among the 3 groups. Compared with the TD group

the AR group and the mixed group showed decrease in the MoCA total score

language item and delayed memory item (P0.05)

and there was no statistical difference between the AR group and the mixed group (P0.05). The incidence of cognitive dysfunction could be screened by MMSE and MoCA scales

and there was statistically significant difference among the 3 groups (P0.05).       Conclusion      The overall cognitive function of the mixed subtype and AR subtype of PD is significantly lower than that of the TD subtype

and the language and delay memory declines are more significant.