Objective      To compared the efficiency of biological glue and suturing in the treatment of rabbit model of renal trauma.       Methods      Thirty-two rabbits were inflicted with partial nephrectomy or excision wound in the left kidney after resection of the right kidney

and then randomly divided into 2 groups

the biological glue group and suture treated group (n=8 for each damage model). Their bleeding amount

hemostatic time

and serum creatinine level before and in 1

2

3 and 4 weeks after surgery were recorded. Ultrasound imaging was performed on the injured left kidney in 1 week after surgery. Histological observation was carried out on the wound site of the kidney.        Results      For the rabbits of renal excision injury

the blood loss was 3.09±0.56 and 5.77±1.33 mL respectively for the animals treated by biological glue and by suturing

and the hemostatic time was 10.02±1.48 and 66.40±6.35 s

respectively. For the rabbits suffering from partial nephrectomy

the blood loss was 4.67±0.73 and 7.42±1.65 mL

and the hemostatic time was 16.16±3.51 and 179.38±18.72 s

respectively for the biological glue group and the suturing group. The blood loss was obviously less and hemostatic time was significantly shorter in the biological glue group than the suturing group (P0.05). Serum levels of creatinine were significantly lower at every time points in the biological glue group than the suturing group of no matter partial nephrectomy or excision wound models (P0.05).  Pathological results showed biological glue group had better wound healing

and significantly mild renal unit damage than the suture group.       Conclusion      Biological glue is superior to suturing in renal unit damage and renal function after renal trauma

and has better hemostatic effect. So it is safe and effective hemostatic method.