Objective      To investigate optional therapeutic strategies for suspected Pneumocystsis carinii pneumonia (PCP) and/or cytomegalovirus (CMV) pneumonia by microbial screening and control experiment.       Methods      Microbial screening included 3 parts

which were microbiological microscopy for patients’ lung specimens and bronchoalveolar lavage fluid (BALF)

detection of serum CMV antibody by ELISA and detection of serum CMV DNA content by fluorescence quantitative PCR. The patients who were positive to only CMV or PCP were respectively di

vided into 2 groups

that is

the combined treatment group and the single treatment group (CMV or PCP as corresponded). The length of hospital stay and the remission rate after 14 days'treatment were compared between the 2 groups.       Results      There were totally 136 positive patients

including 17 only positive to CMV

21 only to PCP and 98 with double positive of PCP and CMV. The length of hospital stay were shorter in the combined treatment group than the single treatment groups (W=162.5

P=0.006). The remission rate were also obviously higher in the former than the latter groups (χ

2

=6.454

P=0.011).       Conclusion      It is quite common for mixed infection of PCP and CMV pneumonia

but rare for single infection. So

the combined treatments are more effective than the single one.