Objective      To compare the clinical characteristics of different subtypes of focal cortical dysplasia (FCD) at human temporal lobe according to 2011 International League Against Epilespy (ILAE) classification.       Methods      Totally

241 cases of temporal lobe epilepsy were divided into different pathological subtypes of FCD according to 2011 ILAE classification. The clinical characteristics including epileptic seizure starting age

epilepsy duration

surgery age

seizure frequency

etc. were analyzed.       Results      Among 92 patients with FCD

the epileptic seizure average age of the associated FCD was 19.2 years old

significantly older than that of the isolated FCD

with statistically significant difference (P=0.038). In the patients with associated FCD

the epileptic seizure average age of FCD Ⅲc was 30.7 years old

significantly older than that of other subtypes of associated FCD(P=0.007). The average epilepsy duration of the associated FCD was 7.8 years

significantly shorter than that of the isolated FCD(P=0.003). In different pathological subtypes of the associated FCD

the epilepsy duration of FCD Ⅲb was 3.5 years（P=0.016）

and that of FCD IIIc was 5.3 years（P=0.041）. Average surgery age of FCD Ⅲc was 35.8 years old

significantly later than that of other subtypes of associated FCD（P=0.014）.       Conclusion      The epileptic seizure average age of the associated FCD is late

especially FCD IIIc. The average epilepsy duration of the associated FCD is short

especially FCD IIIb and FCD IIIc. In the patients with associated FCD

the average surgery age of FCD IIIc is significantly later than that of other subtypes of associated FCD. The isolated FCD and associated FCD show different clinical characteristics.