Tissue defect or deformity seriously affects the patient’s appearance and activity

even his/her mental and physical health. In order to repair tissue defect and deformity

tissue transplantation

tissue substitute (biomaterials)

and tissue engineering technique are rapidly developed in recent years. Many types of biomaterials and tissue engineered materials have been adopted to repair skin and soft tissue defect

and to be applied in augmentation for soft tissue deformity

and also deep tissue damage

including burn and plastic surgery

as well as other clinical disciplines. Common biomaterials and tissue engineered materials include wound dressing

silicone rubber

expanded polytetrafluoroethylene

high density polyethylene

hyaluronic acid for soft tissue repair

and also hydroxyapatite for hard tissue repair. This paper summarized the application and progress of the materials mentioned above.