Lu Xingchen,Dong Chenhui,Du Quanyin,Wang Ziming,Wang Yu,Wang Aimin.Timing of surgery for hip fracture and outcomes in nonagenarians[J].J Amry Med Univ (J Third Mil Med Univ),2015,37(02):158-163.
Lu Xingchen,Dong Chenhui,Du Quanyin,Wang Ziming,Wang Yu,Wang Aimin.Timing of surgery for hip fracture and outcomes in nonagenarians[J].J Amry Med Univ (J Third Mil Med Univ),2015,37(02):158-163.DOI:
Timing of surgery for hip fracture and outcomes in nonagenarians
n=27)、延迟手术组(入院后48~72 h手术,n=18)、晚期手术组(入院后72 h以后手术,n=30)。入院后对患者进行全面评估后,身体条件好者早期手术治疗;身体条件差、基础疾病严重者适当延迟手术,给予损害控制。搜集并分析患者相关临床指标,包括术前评估情况、基础疾病、手术相关指标等,比较术后住院期间并发症情况、不同时期死亡率、生存曲线的异同。 结果 早期、延迟和晚期手术组原发病数量分别为(3.04±1.91)、(4.06±1.59)、(4.13±1.61)种,晚期手术组多于早期手术组(P=0.019);心源性基础疾病分别为6、4、15例,晚期手术组高于早期手术组和延迟手术组(P=0.044);伤前生活能力评分(activities of daily living,ADL)分别为(68.89±8.70)、(67.50±8.95)、(62.83±7.73)分,晚期手术组明显低于早期手术组(P=0.008)。晚期手术组住院时间多于早期手术组和延迟手术组(P0.05)。3组患者性别,年龄,ASA分级,骨折类型,麻醉方式,手术方式等一般情况以及术后住院期间并发症发生率,术后第1、3、6个月死亡率,生存曲线相比,差异无统计学意义(P0.05)。 结论 对基础疾病严重、身体条件差的90岁以上髋部骨折患者适当推迟手术同时全面评估其风险、纠正机体紊乱是安全、有效的,其术后生存状况可达到与身体条件较好的早期手术患者等同的水平。
Abstract
Objective To study the influence of timing of surgery on postoperative curative effect in nonagenarians with hip fracture. Methods A total of 75 nonagenarians with hip fracture in our department from January 2002 to February 2014 were enrolled and retrospectively analyzed. There were 21 males and 54 females with a mean age of 92.35±2.60 (ranged from 90 to 99). There were 34 cases of femoral neck fracture and 41cases of intertrochanteric fracture. All the patients were divided into 3 groups: an early surgery group (operated within 48 h
n=27)
a delayed surgery group (operated between 48 and 72 h
n=18) and a late surgery group (operated after 72 h
n=30). After admission
the relatively healthy nonagenarians received early surgery
while the fragile ones received appropriate postponement and damage control surgery. Clinical indicators such as preoperative assessments
comorbidities
operation related indexes
and so on were collected and analyzed. The mortalities
complications and survival curves during postoperative hospitalization were compared. Results The mean types of comorbidities in the early
delayed and late surgery groups were 3.04±1.91
4.06±1.59
and 4.13±1.61
respectively
and the number of the late surgery group was higher than that of the early surgery group (P=0.019). The cardiac disease rate of the late surgery group (4 cases) was higher than that (3 cases) of the early surgery group and that (1 case) of the delayed surgery group (P=0.044). The before-injury activities of daily living (ADL) scores of the early
delayed and late surgery groups were 68.89±8.70
67.50±8.95
and 62.83±7.73
respectively
and the scores of the late surgery group were lower than those of the early surgery group (P=0.008). The patients in the late surgery group experienced relatively long hospitalization period (P0.05). There were no statistically significant differences in the gender
age
American society of anesthesiologists (ASA) classification
type of hip fracture
anesthesia manner and operation manner among the three groups (P0.05). The incidences of complications and mortalities in 1
3 and 6 months after surgery showed no significant differences among the 3 groups (P0.05)
as well as the survival curves (P=0.253). Conclusion Appropriate postponement and damage control surgery is safe and effective for alleviating major clinical abnormalities before surgery
by which the survival conditions of the fragile nonagenarians can reach the levels of the relatively healthy ones.
Establishment and validation of a risk prediction model for postoperative delirium in elderly patients after individualized hip fracture surgery
Effect of glutamine fortified enteral nutrition preparation on tolerance of early postoperative nutritional support and inflammatory response in the elderly after hip fracture surgery