Objective      To analyze the diagnosis and treatment of 5 cases of confirmed Ebola virus disease (EVD) and provide scientific basis for better prevention and treatment of the disease.       Methods      Clinical data of 5 confirmed EVD patients admitted in our Ebola Treatment Center（ETC） from December 5

2014 to January 17

2015 were collected in this study. Their epidemiological history

symptoms

signs

laboratory results and treatment outcome were retrospectively analyzed.       Results      EVD showed obvious family aggregation

with 3 patients from 2 families in the cohort. There were 3 cases who were negative to PCR test for the first time

but positive for the second time. The most common symptoms were fever

fatigue

vomiting and diarrhea

with few bleeding-related symptoms and signs. Though early symptomatic and support treatment

such as antifebrile and infusion therapies

3 patients were fully recovered and discharged

and the other 2 died.       Conclusion      For the suspected patients with contact history but negative PCR result for the first time

another test must be taken in 72 h later. Support therapies are commonly applied in the treatment of EVD

focusing on correcting water and electrolyte disorders

maintaining homeostasis

and preventing complications.