Analysis of willingness to participate in clinical trials using antiviral drugs for HIV prevention among those with HIV-infected regular sexual partners

何佳桐; 高菲菲; 钟晓妮; 彭斌; 张燕; 戴江红; 宋本莉; 黄爱龙

您当前的位置：

首页 >

文章列表页 >

Analysis of willingness to participate in clinical trials using antiviral drugs for HIV prevention among those with HIV-infected regular sexual partners

更新时间：2026-01-09

- Analysis of willingness to participate in clinical trials using antiviral drugs for HIV prevention among those with HIV-infected regular sexual partners
- Journal of Army Medical University Vol. 36, Issue 2, Pages: 164-169(2014)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC： R181.22;R512.710.1;R978.7
- Published：2014
- 稿件说明：
移动端阅览
何佳桐,高菲菲,钟晓妮,彭斌,张燕,戴江红,宋本莉,黄爱龙.HIV感染者的固定性伴服用抗病毒药物预防艾滋病临床试验参与意愿研究[J].陆军军医大学学报(原第三军医大学学报),2014,36(02):164-169.

　He Jiatong,Gao Feifei,Zhong Xiaoni,Peng Bin,Zhang Yan,Dai Jianghong,Song Benli,Huang Ailong.Analysis of willingness to participate in clinical trials using antiviral drugs for HIV prevention among those with HIV-infected regular sexual partners[J].J Amry Med Univ (J Third Mil Med Univ),2014,36(02):164-169.
何佳桐,高菲菲,钟晓妮,彭斌,张燕,戴江红,宋本莉,黄爱龙.HIV感染者的固定性伴服用抗病毒药物预防艾滋病临床试验参与意愿研究[J].陆军军医大学学报(原第三军医大学学报),2014,36(02):164-169. DOI：

　He Jiatong,Gao Feifei,Zhong Xiaoni,Peng Bin,Zhang Yan,Dai Jianghong,Song Benli,Huang Ailong.Analysis of willingness to participate in clinical trials using antiviral drugs for HIV prevention among those with HIV-infected regular sexual partners[J].J Amry Med Univ (J Third Mil Med Univ),2014,36(02):164-169. DOI：

摘要

目的了解我国四川、新疆两地HIV感染者的固定性伴（HIV-negative regular sexual partners，PARs）服用抗病毒药物预防艾滋病临床试验参与意愿及影响因素。方法通过横断面调查的方法，采用单因素和多因素Logistic回归进行影响因素分析。结果本研究共纳入396名PARs，其中仅12.88%的PARs听说过药物预防措施，经调查员讲解后，愿意参与临床试验的占85.86%。多因素分析结果显示，参与意愿的影响因素为户口(农村/城市：AOR=4.269

=0.000 5）；自认为感染艾滋病的可能性（大/小：AOR=2.509

=0.022 1；一般/小：AOR=2.338

=0.048 4）；近半年，最近1次与阳性性伴发生性行为时安全套使用情况（发生性行为未使用安全套/未发生性行为：AOR=10.451

=0.029 4）;阳性性伴的用药态度（支持/不太清楚及反对: AOR=2.079

=0.042 9）。结论 PARs临床试验参与意愿较高，参与意愿受户口、自身风险认知以及社会支持的影响。

Abstract

Objective To investigate the willingness and its influencing factors to participate in the clinical trials which take antiviral drugs to prevent HIV among the HIV-negative persons whose regular sexual partners were HIV-infected persons (PARs) in Sichuan and Xinjiang

China. Methods A cross-sectional survey was conducted and influencing factors were analyzed by univariate and multivariate logistic regression. Results Totally 396 qualified subjects were

recruited

of which 12.88% had ever heard and 85.86% were willing to participate in the clinical trials of HIV prevention. Household registration (rural/urban: AOR=4.269

=0.000 5)

self-awareness of HIV infection risk (high/low: AOR=2.509

=0.022 1; moderate/low: AOR=2.338

=0.048 4)

using condoms or not when having sex with HIV-infected partners in the nearly six months (not using/not having sex: AOR=10.451

=0.029 4)

and attitude to HIV-infected partners to medication (support/not support or unsure: AOR=2.079

=0.042 9) were screened by multivariate analysis. Conclusion The willingness is relatively high

which is affected by household registration

self-risk cognition and social support.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Clinical trial design for revascularization in acute stroke due to anterior circulation large vessel occlusion: a comparative study on 6 trials

Analysis of clinical trials carried out by U.S. Army Medical Research and Materiel Command based on ClinicalTrials.gov data

Efficacy and safety of rasagiline mesylate in treatment of idiopathic Parkinson’s disease with motor fluctuations: a randomized, double-blind, parallel-controlled, single-center trial

Analysis on willingness to participate in pre-exposure prophylaxis clinical trial in female sex workers

Analgesic efficacy of 10-mg morphine sulfate suppository on severe chronic cancer pain and its adverse reactions: clinical analysis of 64 cases

Related Author

伍亚舟

陈济安

资文杰

武书兴

易大莉

张玉华

阎少多

赵慧

Related Institution

No data

⁰