Analysis on willingness to participate in pre-exposure prophylaxis clinical trial in female sex workers

高菲菲; 钟晓妮; 彭斌; 张燕; 梁浩; 邹云峰; 戴江红; 宋本莉; 刘倩萍; 黄爱龙

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Analysis on willingness to participate in pre-exposure prophylaxis clinical trial in female sex workers

更新时间：2026-01-09

- Analysis on willingness to participate in pre-exposure prophylaxis clinical trial in female sex workers
- Journal of Army Medical University Vol. 35, Issue 3, Pages: 255-259(2013)
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  CLC： R167;R181.23;R183
- Published：2013
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高菲菲,钟晓妮,彭斌,张燕,梁浩,邹云峰,戴江红,宋本莉,刘倩萍,黄爱龙.女性性工作者艾滋病暴露前预防用药临床试验参加意愿分析[J].陆军军医大学学报(原第三军医大学学报),2013,35(03):255-259.

　Gao Feifei,Zhong Xiaoni,Peng Bin,Zhang Yan,Liang Hao,Zou Yunfeng,Dai Jianghong,Song Benli,Liu Qianping,Huang Ailong.Analysis on willingness to participate in pre-exposure prophylaxis clinical trial in female sex workers[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(03):255-259.
高菲菲,钟晓妮,彭斌,张燕,梁浩,邹云峰,戴江红,宋本莉,刘倩萍,黄爱龙.女性性工作者艾滋病暴露前预防用药临床试验参加意愿分析[J].陆军军医大学学报(原第三军医大学学报),2013,35(03):255-259. DOI：

　Gao Feifei,Zhong Xiaoni,Peng Bin,Zhang Yan,Liang Hao,Zou Yunfeng,Dai Jianghong,Song Benli,Liu Qianping,Huang Ailong.Analysis on willingness to participate in pre-exposure prophylaxis clinical trial in female sex workers[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(03):255-259. DOI：

摘要

目的了解我国重庆、四川、广西、新疆女性性工作者(female sex workers

FSWs)对暴露前预防用药(pre-exposure prophylaxis

PrEP)临床试验的参加意愿及其影响因素。方法采用非随机抽样，对研究对象进行面对面匿名问卷调查。采用χ

检验进行单因素分析，利用Logistic回归进行多因素分析。结果共征集到1 340名合格的研究对象。我国四川、重庆、广西和新疆的FSWs对PrEP的知晓率为15.27%，进行PrEP相关内容的讲解后，FSWs人群PrEP的临床试验的参加意愿为56.49%。经Logistic回归分析，FSWs人群PrEP临床试验参加意愿的影响因素包括调查现场（四川/广西：OR=0.471，P=0.000 1；新疆/广西：OR=1.971，P0.01）；认为预防艾滋病困难吗（不困难/困难：OR=1.507，P=0.009 0）；是否会主动提出使用安全套（是/否：OR=1.645，P=0.014 5）；对方不使用安全套，是否拒绝发生性行为（是/否：OR=1.506，P=0.008 8）；是否应在性工作者中推广PrEP（是/否：OR=2.105，P0.01）；是否会建议朋友使用PrEP（是/否：OR=1.642，P=0.035 9）。结论我国重庆、四川、广西、新疆的FSWs人群对PrEP临床试验的参加意愿相对较高。

Abstract

Objective To understand the willingness to participate in pre-exposure prophylaxis (PrEP) clinical trial and the influencing factors among female sex workers (FSWs) in Chongqing

Sichuan

Guangxi and Xinjiang. Methods Face-to-face anonymous questionnaire was conducted in 1 340 qualified objects by non-randomly sampling method. Chi square test was employed to conduct univariate analysis

and multivariate analysis was conducted using logistic regression. Results The awareness rate of PrEP among FSWs was 15.27% and elevated to 56.49% after being taught on PrEP-related knowledge by investigators. Logistic regression showed that the factors influencing the willingness to participate PrEP clinical trial among FSWs were survey sites (Sichuan/Guangxi: OR=0.471

P=0.000 1; Xinjiang/Guangxi: OR=1.971

P0.01)

self-awareness of difficulty in preventing AIDS (not difficult/difficult: OR=1.507

P=0.009 0)

whether offering to use condoms or not (yes/no: OR=1.645

P=0.014 5)

whether refusing to have sex or not if the male did not use condoms (yes/no: OR=1.506

P=0.008 8)

whether should promoting PrEP in female sex workers or not (yes/no: OR=2.105

P0.01)

and whether would recommending friends to use PrEP or not (yes/no: OR=1.642

P=0.035 9). Conclusion The willingness to participate in PrEP clinical trial among FSWs in Chongqing

Sichuan

Guangxi and Xinjiang are relatively high.

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