Objective        To explore the treatment methods for the wounds of congenital skin defect.       Methods       In 38 patients with congenital skin defect

18 patients with wound area less than 10% were bandaged and dressing changed (membrane was removed in 13 patients and remained in 5 patients)

1 patient with wound area of 7% was bandaged

dressing changed and grafted with big piece razor thin autoskin

16 patients with wound area more than 10% were grafted of big piece razor thin autoskin

and 3 patients complicated with skull defects were grafted with artificial dermis and big piece razor thin autoskin. A long-term follow-up was carried out

and the curative effects of the three treatment methods were summarized.        Results        All of the 38 patients got favorable recovery

and 31 patients were followed up for 5 months to 7 years. The wound healing of the 5 patients who were bandaged and dressing changed with membrane were quicker than that of those without membrane. Three patients had pigment dimmed but no obvious scars

and 2 patients had light scars. The 9 patients without membrane all had different degrees of scars with dimmed pigment. In the 15 patients receiving big piece razor thin autoskin grafting

5 patients had no scars

5 patients had light scar

and 5 patients had different degree of hyperplastic scars. The 3 patients complicated with skull defects treated by artificial dermis and big piece razor thin autoskin grafting all had light scars with no hair

but the skull defects were cured.       Conclusion        Membranes of wounds were epidermis of maldevelopment and can promote wound healing. Wound area less than 10% leads to good efficacy by bandaged and dressing changed with membrane

while wound area more than 10% suggests big piece razor thin autoskin grafting to avoid severe complication. In wounds complicated with skull defects

skull defects need not to be treated.