Zhang Shaojie,Chen Jianghua,Gan Shufen,Yan Guohui.Speckle tracking imaging in assessment for global and regional systolic function in left ventricle in patients with coronary artery disease[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(02):165-168.
Zhang Shaojie,Chen Jianghua,Gan Shufen,Yan Guohui.Speckle tracking imaging in assessment for global and regional systolic function in left ventricle in patients with coronary artery disease[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(02):165-168.DOI:
Speckle tracking imaging in assessment for global and regional systolic function in left ventricle in patients with coronary artery disease
Objective To evaluate the clinical value of speckle tracking imaging(STI) by quantitatively analyzing longitudinal strain and left ventricular torsion in patient with coronary heart disease (CHD). Methods Thirty patients who had at least one branch of coronary arteries with stenosis over 75% identified with angiography and admitted in Department of Cardiology of our hospital during February to April 2011 were enrolled in this study. Another 25 sex- and age-matched healthy volunteers served as normal control. They all underwent STI examination. Two-dimensional images of the apical long-axis view
four-chamber view
two-chamber view and left ventricular short-axis view at the levels of mitral annulus and apex were recorded. Longitudinal strain
average total strain
left ventricular torsion
torsion rate and time to peak were measured. Results In control group
the longitudinal strain was increased along with the distance from the base (P0.05). While
CHD patients showed significant reduction in the longitudinal strain
with the longitudinal strain of different sections and the average total strain significantly lower than those in the normal control (P0.05). The average total strain value of -19% had a sensitivity of 86.4% and a specificity of 83.3% when it was used to identify ≥75% coronary lesion. CHD patients showed significant reduction in the torsion
torsion rate
and significantly delayed time to peak(P0.05). Conclusion STI is a simple and reliable new method for clinical evaluation of LV regional and global systolic function in patient with CHD.