Objective      To investigate the clinical data of fresh frozen plasma (FFP) transfusions in 3 Class-AAA hospitals in order to grasp clinical transfusion.       Methods      We investigated and analyzed medical records of patients who had received FFP transfusions in Sichuan Provincial People’s Hospital

Xinqiao Hospital

and General Hospital of Chengdu Military Command during January to December 2009. Indexes included total volume of FFP

average volume

situations of using FFP in different departments and the standard coagulation tests in these patients.       Results      In this investigation

5 570 FFP transfusions were given to 2 036 patients

with a total volume of 21 062.9 U. Among these patients

49.1% of them had received FFP transfusion only once

and 14.5% had received no more than 2 U plasma. There was a significant difference in average doses of each FFP transfusion between surgical departments and non-surgical departments (P0.05). Patients from departments of thoracic surgery

gastroenterology and orthopedics received more FFP than patients in other departments. There were 191 patients (9.4%) getting FFP transfusions in absence of prothrombin time (PT) records

and 224 patients (11.0%) without activated partial thromboplastin time (APTT) records. The median reductions in PT were shorter when the baseline pre-FFP transfusion PT was longer than 50 s. FFP had little effect on APTT.       Conclusion      Some clinical use of plasma is not adequate. There is a significant difference in FFP doses of transfusions among different departments. FFP transfusion exerts therapeutic effect on the patients with prolonged PT or APTT.