Yang Zhi,Shen Liru,Shi Xiaohua,Zhang Yiming,Fan Dongli.Surface properties and cell compatibility of carbon ion implanted silicone rubber[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(02):123-126.
Yang Zhi,Shen Liru,Shi Xiaohua,Zhang Yiming,Fan Dongli.Surface properties and cell compatibility of carbon ion implanted silicone rubber[J].J Amry Med Univ (J Third Mil Med Univ),2013,35(02):123-126.DOI:
Surface properties and cell compatibility of carbon ion implanted silicone rubber
physicochemical properties and cell compatibility of silicone rubber (SR) after carbon ion being injected to its surface. Methods Different volumes of carbon ion injection was injected into the surface of SR with the aid of a multi-function ion injection machine. The obtained SR was named as carbon-silicone rubber(C-SR). Scanning electron microscopy(SEM)
Fourier transform infrared spectrometry(FTIR) and X-ray diffraction(XRD) were used to analyze the surface properties of modified materials. Cell proliferation
immunofluorescence staining and Western blot analysis were used to analyze the biocompatibility of modified materials after cocultured with human dermal fibroblasts. Results SEM and FTIR indicated that there was no any obvious difference in the morphology of the surface of modified C-SR. XRD showed that a new crystal structure was formed on the surface of the modified material after carbon-ion implantation
but the changes were not obvious compared with original materials. Cell proliferation experiment illustrated that human dermal fibroblasts grow better in C-SR than in SR(P0.05). Immunofluorescence staining and Western blotting indicated that the expression of vinculin was enhanced in the C-SR materials
indicating that the carbon-ion implantation increased the cell adhesion. Conclusion Carbon-ion implantation to SR improves the surface properties and cell compatibility. C-SR might be used as a new filling material of soft tissue.