Objective　　　 To determine the effect of laparoscopic Roux-en-Y gastric bypass on blood pressure in patients with type 2 diabetes.　　　 Methods　　　 Clinical data of 21 cases of patients with T2DM undergoing Roux-en-Y gastric bypass in our department after medical assessment during 2010 to 2012 were collected in this study. Their office blood pressure and 24-hour ambulatory blood pressure (ABPM) before and in 1

3

6

and 12 months after surgery were recorded

and the correlation between their changes with body weight

body mass index (BMI

)

waist circumference (WC) were analyzed.　　　 Results　　　 Compared with pre-operation

the office blood pressure and morning blood pressure surge (MBPS) were decreased significantly (P0.05) in the obese group (BMI ≥28.0 kg/m

2

). In non-obese group only the diastolic blood pressure was decreased after surgery (P0.05)

and had no significant difference in ABPM before and after surgery. Compared with pre-operation

office blood pressure was decreased significantly in patients with both T2DM and hypertension (P0.05). Moreover

there was no significant correlation between the changes of office blood pressure and the changes of body weight

BMI

and WC before and after operation.　　　 Conclusion　　　 For T2DM patients with hypertension

laparoscopic Roux-en-Y gastric bypass decreases the early post-operative blood pressure significantly

and there is no significant correlation between the changes of blood pressure and the changes of body weight

BMI

and WC.