The prevalence of cardiometabolic diseases such as hypertension and diabetes is increasing rapidly in worldwide. The conventional treatments of these diseases are limited due to multiple clusters of cadiometabolic disturbances. Furthermore

little attention is paid to the relationship between gastrointestinal tract dysfunction and the development of cardiometabolic diseases. In recent years

some clinical studies confirmed that metabolic surgery on gastrointestinal tract could prevent effectively and even cure cardiometabolic disease clinically. Thus

this novel intervention highlights an important role of gastrointestinal tract in the pathogenesis of cardiometabolic diseases

and further implicates metabolic surgery as a potential therapeutic strategy in the treatment of cardiometabolic diseases.