Objective      To observe the metaphase clinical outcome of transanal endorectal pull-through colorectal resection and oblique anastomosis in patients with Hirschsprung’s disease (HD).       Methods      One hundred and five patients with rectosigmoid HD

who underwent transanal endorectal pull-through colorectal resection and oblique anastomosis

were regularly followed up after operation to observe their defecation.       Results      No patient died

no blood was transfused and no complication occurred during the operation. The average operation time was 74.6 min

71.6 min

77.9 min

and 112.5 min

respectively

for the patients at the age of 0-3 months

3-12 months

1-3 years

3 years. Their average intra-operative blood loss was 12.5 ml

16 ml

20 ml

and 40 ml

respectively. No infection

anastomotic fistula and fissuration occurred after operation. Sixty patients were followed up for 6-40 months during which contaminated stool was noted in 5 patients

all the patients with normal urine

and no  abdominal distension

constipation

neurotic bladder

and anal stricture. Of the male patients

52 showed an erection function of penis. Enterocolitis was found in 4 patients about 2 months after operation. Of the 28 patients who underwent anorectal manometry

only 4 had RAIR reflection and 1 had almost normal RAIR reflection.       Conclusion      Transanal endorectal pull-through colorectal resection and oblique anastomosis can achieve good defecation in HD patients with the advantages of less trauma

shorter operation time

preservation of rectal receptor

rapid recovery

few complications

and satisfactory metaphase clinical outcome.