Objective      To investigate the effect of cutting chiasm of crus penis on erectile dysfunction in rats.       Methods      One hundred and thirty-five male Wistar rats at procreative period were randomly divided into a chiasm of crus penis cutting group (n=25)

a chiasm of crus penis+one-side ischiocavernosus cutting group (n=25)

a one-side ischiocavernosus cutting group (n=25)

a double-side ischiocavernosus cutting group (n=25)

a sham operation group (n=25) and a normal group (n=10). Another 135 female Wistar rats at procreative period were picked out to match with the male rats one-to-one randomly

and the records of the pregnancy of these female rats were observed after 2 months. Meanwhile

erectile dysfunction of the male rats was inferred from the records of the pregnancy of their matched female rats.       Results      Three male rats died in the chiasm of crus penis cutting group. The effective paired female rats were 22 and all of them got pregnancy (100%). Two male rats died in the chiasm of crus penis+one-side ischiocavernosus cutting group. The effective paired female rats were 23

and none of them got pregnancy (0%). Four male rats died in the one-side ischiocavernosus cutting group. The effective paired female rats were 22

and 21 of them got pregnancy (95.5%). Three male rats died in the double-side ischiocavernosus cutting group. The effective paired female rats were 24

and none of them got pregnancy (0%). Two male rats died in the sham operation group. The effective paired female rats were 23

and all of them got pregnancy (100%). No male rat died in the normal group and all of the 10 female rats got pregnancy (100%). The differences between the normal group

sham operation group

one-side ischiocavernosus cutting group and chiasm of crus penis cutting group were not significant (P0.05). The differences were significant when the chiasm of crus penis cutting group compared with the chiasm of crus penis+one-side ischiocavernosus cutting group and the double-side ischiocavernosus cutting group (P0.05)

but the differences between the chiasm of crus penis+one-side ischiocavernosus cutting group and the double-side ischiocavernosus cutting group were not significant (P0.05).       Conclusion      Erectile dysfunction can be achieved by cutting the chiasm of crus penis and one-side ischiocavernosus rather than merely cutting the chiasm of crus penis.