Liu Zhihua,Qian Xuehua,Zhou Tingyong,Lu Fajin,Zheng Dengru,Li Linhong,Bai Guiqin,Zhang Hua.Measurement of hippocampal morphology in human brain by MRI[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(16):1636-1641.
Liu Zhihua,Qian Xuehua,Zhou Tingyong,Lu Fajin,Zheng Dengru,Li Linhong,Bai Guiqin,Zhang Hua.Measurement of hippocampal morphology in human brain by MRI[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(16):1636-1641.DOI:
Measurement of hippocampal morphology in human brain by MRI
Objective To provide linear measurement indices for hippocampal morphological change-related diseases. Methods The head magnetic resonance images of 51 healthy adults in the First Affiliated Hospital of Chongqing Medical University were analyzed. The volume
height
width and length of the hippocampus were measured
and the correlation of hippocampal volume with the height
width and length of the hippocampus were statistically analyzed after standardization. Results The standardized volume and length of hippocampal head
body and tail
standardized hippocampal volume
standardized length of hippocampal longitudinal axis
standardized hippocampal width and standardized temporal horn width were significantly greater in the females than in the males (P0.05
P0.01)
but the interuncal distance and the temporal horn width were significantly greater in the males than in the females (P0.05
P0.01). The standardized length of hippocampus head and tail were greater at the right side than at the left side (P0.05)
while the standardized length of hippocampal body and hippocampal longitudinal axis were greater at the left side than at the right side (P0.05). Pearson correlation analysis demonstrated that the liner indices which were the most closely correlated with hippocampal volume after standardization were the width of hippocampus
the length of hippocampal longitudinal axis
the width of temporal horn and the volume of hippocampal tail. Conclusion There are significant distinctions of hippocampal morphology in sex and side
which should be noted in clinical practice. The width of the hippocampus and the length of hippocampal longitudinal axis can be used as preliminary screening indices for morphological changes of hippocampus.