Objective      To explore the clinical efficacy of hemispherectomy for pediatric intractable epilepsy.       Methods      Hemispherectomy was conducted in 25 pediatric patients with intractable epilepsy and unilateral extensive hemispheric lesions between 2005-2010. A retrospective analysis of the clinical data

surgical outcomes and follow-up results of these pediatric patients were performed.       Results      The seizures of all the patients were effectively controlled. Twenty-three patients achieved Engel class Ⅰ outcome

and 2 patients achieved Engel class Ⅱ outcome. No significant exacerbation of neurological deficits was observed in all the patients. The postoperative EEG was normal in 23 patients

and was significantly improved in 2 patients. The postoperative MRI showed the contralateral hemisphere enlarged and extended to ipsilateral hemisphere.        Conclusion      For the pediatric intractable epilepsy induced by unilateral extensive hemispheric lesions

hemispherectomy shows good surgical outcomes.