Endovascular embolization combined with Gamma Knife in the treatment of cerebral arteriovenous malformations

黄昌仁; 耿明英; 江涌; 陈礼刚; 李玉伟; 唐光才; 韩福刚; 沈光建

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Endovascular embolization combined with Gamma Knife in the treatment of cerebral arteriovenous malformations

更新时间：2026-01-09

- Endovascular embolization combined with Gamma Knife in the treatment of cerebral arteriovenous malformations
- Journal of Army Medical University Vol. 34, Issue 6, Pages: 561-563(2012)
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  CLC： R743.405;R459.9;R61
- Published：2012
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黄昌仁,耿明英,江涌,陈礼刚,李玉伟,唐光才,韩福刚,沈光建.血管内栓塞与伽玛刀结合治疗86例脑动静脉畸形的临床分析[J].陆军军医大学学报(原第三军医大学学报),2012,34(06):561-563.

　Huang Changren,Geng Mingying,Jiang Yong,Chen Ligang,Li Yuwei,Tang Guangcai,Han Fugang,Shen Guangjian.Endovascular embolization combined with Gamma Knife in the treatment of cerebral arteriovenous malformations[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(06):561-563.
黄昌仁,耿明英,江涌,陈礼刚,李玉伟,唐光才,韩福刚,沈光建.血管内栓塞与伽玛刀结合治疗86例脑动静脉畸形的临床分析[J].陆军军医大学学报(原第三军医大学学报),2012,34(06):561-563. DOI：

　Huang Changren,Geng Mingying,Jiang Yong,Chen Ligang,Li Yuwei,Tang Guangcai,Han Fugang,Shen Guangjian.Endovascular embolization combined with Gamma Knife in the treatment of cerebral arteriovenous malformations[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(06):561-563. DOI：

摘要

目的评价血管内栓塞结合伽玛刀治疗对脑动静脉畸形的治疗作用。方法选择泸州医学院附属医院神经外科从2001年9月至2010年12月86例经数字减影血管造影（digital subtraction angiography

DSA)确诊为脑动静脉畸形的患者

并选择了血管内介入栓塞治疗，其中72例随后又进行了伽玛刀治疗。术后疗效利用DSA/CTA/MRI进行影像学评价。结果 68例获得随访（79.1%），随访时间1~6年，平均2.5年。临床症状康复52例，轻残5例，重残1例，癫痫发作8例，再出血2例，无死亡病例。获得DSA/CTA/MRI影像随访65例（75.6%），其中畸形血管完全消失37例(56.9%)，大部分消失20例(30.8%)，部分消失8例(12.3%)。结论血管内栓塞结合伽玛刀对脑动静脉畸形的治疗具有疗效较好、并发症少、创伤小、安全性高和可重复性等优点。伽玛刀还可以作为手术切除的前期治疗。

Abstract

Objective To evaluate the therapeutic effect of endovascular embolization combined with Gamma Knife in the treatment of cerebral arteriovenous malformations (AVMs). Methods Clinical data of 86 patients suffering from cerebral AVMs confirmed by digital subtraction angiography (DSA) in the neurosurgery department

Affiliated Hospital of Luzhou Medical College from September 2001 to December 2010 were analyzed retrospectively. All the patients were treated with endovascular embolization

after which 72 patients were treated with Gamma Knife. The postoperative therapeutic effects were evaluated by DSA

computed tomography angiography (CTA) and MRI. Results The follow-up was achieved in 68 patients (79.1%) for 1-6 years (average 2.5 years)

with apparent symptom relief in 52 patients

mild disability in 5 patients

severe disability in 1 patient

seizure episodes in 8 patients

recurrent hemorrhage in 2 patients

and no death. The follow-up of DSA

CTA and MRI in 65 patients (75.6%) showed complete AVM disappearance in 37 patients (56.9%)

most AVM disappearance in 20 patients (30.8%) and part AVM disappearance in 8 patients (12.3%). Conclusion Endovascular embolization combined with Gamma Knife

which is minimally invasive and repeatable

is a safe and effective therapy in treatment of cerebral AVMs

and Gamma Knife can also be applied as an early therapy before the operation.

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